ANCOVA versus Multilevel Random Coefficient Models/HLM/mixed regression

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ANCOVA versus Multilevel Random Coefficient Models/HLM/mixed regression

leah rubin
Hi,

We conducted a randomized clinical trial with 4 treatment groups (3 active treatments and placebo) and baseline and 1-year.
Our primary interest was in examining differences in linear rates of change between each of the active treatment groups and the placebo group on select outcome measures from baseline to 1-year. I conducted a multilevel random coefficient model and included a random intercept to account for individual differences at baseline. Is this statistical method better than conducting ANCOVAs where the final score is the dependent measure and the baseline value as the covariate? Any input and/or pertinent references to this issue would be greatly appreciated.

Thanks in advance,
Leah