How to get significant STR markers

[Errol Bagaipo]

Hi All,

Thank you for letting me join to this group.

I have around 400 str/microsatellite markers and 380 individuals. The individuals are grouped into 2 categories: Group1 and Group2. Some of the individuals are 80% or 90% genotyped only but most of individuals are 95% to 99% already genotyped. My first problem is how to get the statistically significant markers.

Please help.

Thanks,


Errol

[ro]

Hi

I maybe did not understand 100% your answer but maybe you should use more
polymorphic markers...

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[David Marso]

"My first problem is how to get the statistically significant markers."
How is this concept defined within the dominant paradigm dictating the best practices of your discipline?
How do others in your field compute such a beast?
Show me the math...  Otherwise you are speaking Greek to a bunch of pagans ;-)
Can you illustrate the concept with a snippet of data, say clearly explicate what differentiates a statistically significant marker from a statistically non-significant marker?

Errol Bagaipo wrote

Hi All,

Thank you for letting me join to this group.

I have around 400 str/microsatellite markers and 380 individuals. The
individuals are grouped into 2 categories: Group1 and Group2. Some of the
individuals are 80% or 90% genotyped only but most of individuals are 95% to
99% already genotyped. My first problem is how to get the statistically
significant markers.

Please help.

Thanks,


Errol