hospitals mortality rate

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hospitals mortality rate

Omar Farook
Q: Dear Experts,

I would like to monitor hospital’s mortality rate in our hospital by using p-control chart to see if the rates are within our expectation, according to my knowledge mortality rate equation as follows,

Mortality rate = no. of patients who died / no. of patients admitted.

In a hospital we have a patient who admitted past month e.g. Aug and died in Aug or sometimes in Sep.

My question is, if I would like to calculate mortality, rate let’s say for Aug, are the data for the numerator and denominator should be for Aug only?

Hope I was clear enough and many thanks in advance.

Omar.


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Re: hospitals mortality rate

Richard Ristow
Postscript:

>I'd say this one is fairly clear: the August denominator (admissions)
>should be the patients admitted in August. The August numerator (died)
>should be the number of patients admitted in August who died,
>regardless of when they died.

Meaning, then, that you can't calculate the August rate until all
patients admitted in August have died or been discharged. I don't know
what your maximum length of stay is. I think patients staying over
about 4 weeks need special handling, but my head is fuzzy tonight, and
I can't recommend what.
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Re: hospitals mortality rate

David Wasserman
Alternatively, if one can't wait for all cases to resolve themselves:

Mortality rate for August = (all patients admitted in August who died)/(all
patients admitted in August who died + all patients admitted in August who
have been discharged)

ignoring those who were admitted in August but have neither died nor been
discharged as of the time of calculation.

David Wasserman


----- Original Message -----
From: "Richard Ristow" <[hidden email]>
To: <[hidden email]>
Sent: Sunday, September 24, 2006 7:47 PM
Subject: Re: hospitals mortality rate


> Postscript:
>
>>I'd say this one is fairly clear: the August denominator (admissions)
>>should be the patients admitted in August. The August numerator (died)
>>should be the number of patients admitted in August who died,
>>regardless of when they died.
>
> Meaning, then, that you can't calculate the August rate until all
> patients admitted in August have died or been discharged. I don't know
> what your maximum length of stay is. I think patients staying over
> about 4 weeks need special handling, but my head is fuzzy tonight, and
> I can't recommend what.
>
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Re: hospitals mortality rate

Omar Farook
Dear experts,

Many thanks, the ideas were very valuables; I think the equation of

Mr. Ristow is very difficult to implement, because

in this case may be we needs more than 3 months to wait until all August’s cases resolve (died or discharges).

Omar.


David Wasserman <[hidden email]> wrote:  Alternatively, if one can't wait for all cases to resolve themselves:

Mortality rate for August = (all patients admitted in August who died)/(all
patients admitted in August who died + all patients admitted in August who
have been discharged)

ignoring those who were admitted in August but have neither died nor been
discharged as of the time of calculation.

David Wasserman


----- Original Message -----
From: "Richard Ristow"
To:
Sent: Sunday, September 24, 2006 7:47 PM
Subject: Re: hospitals mortality rate


> Postscript:
>
>>I'd say this one is fairly clear: the August denominator (admissions)
>>should be the patients admitted in August. The August numerator (died)
>>should be the number of patients admitted in August who died,
>>regardless of when they died.
>
> Meaning, then, that you can't calculate the August rate until all
> patients admitted in August have died or been discharged. I don't know
> what your maximum length of stay is. I think patients staying over
> about 4 weeks need special handling, but my head is fuzzy tonight, and
> I can't recommend what.
>



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Re: hospitals mortality rate

Beadle, ViAnn
In reply to this post by Omar Farook
Are you going to request an attributes P or NP chart for this using month as your group? If so, I think that deaths are your defect count and hospital population is your sample size variable. However, since your samples are not discrete--that is a patient might be in the hospital for several months and thus participate in multiple samples--I'd worry about the limits computed. I would have thought that SURVIVAL or Kaplan-Meir is a better approach.

-----Original Message-----
From: SPSSX(r) Discussion [mailto:[hidden email]] On Behalf Of Omar Farook
Sent: Sunday, September 24, 2006 4:05 AM
To: [hidden email]
Subject: hospitals mortality rate

Q: Dear Experts,

I would like to monitor hospital's mortality rate in our hospital by using p-control chart to see if the rates are within our expectation, according to my knowledge mortality rate equation as follows,

Mortality rate = no. of patients who died / no. of patients admitted.

In a hospital we have a patient who admitted past month e.g. Aug and died in Aug or sometimes in Sep.

My question is, if I would like to calculate mortality, rate let's say for Aug, are the data for the numerator and denominator should be for Aug only?

Hope I was clear enough and many thanks in advance.

Omar.


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Re: hospitals mortality rate

Richard Ristow
In reply to this post by Omar Farook
At 01:55 AM 9/25/2006, Omar Farook wrote:

>I think the equation of Mr. Ristow is very difficult to implement,
>because
>in this case may be we needs more than 3 months to wait until all
>August's cases resolve (died or discharges).

Well, then, you have to decide what you MEAN by "August mortality",
starting by ignoring what you can and can't measure.

In one way, apart from difficulties in measuring (the "three months to
wait"), the definition I gave you is correct. What's probably
meaningful to the patients and their families is, if someone is
admitted to this hospital, what's the probability they will (ever) walk
out alive?

It may not be the right measure of hospital performance, though.

>Now, David Wasserman <[hidden email]> suggsted:
>
>>Mortality rate for August = (all patients admitted in August who
>>died)/(all
>>patients admitted in August who died + all patients admitted in
>>August who
>>have been discharged) ignoring those who have neither died nor been
>>discharged.

That's a good idea, but it tacitly assumes that mortality for long-stay
patients is similar to that for short-stay patients; at best, that
can't be relied on. Much more likely, it isn't true.

(I don't think this is a survival-analysis problem, by the way. A
discharged patient isn't 'censored', but favorable-outcome.)

Even if you can wait for all cases to be resolved, that's a problem:
long-stay and short-stay patients likely have different mortality
patterns. You should look, if you haven't. What is the distribution of
your lengths of stay? What's the median, the 90th percentile, the 99th
percentile? For a lot of hospitals, most stays are short, with a 'tail'
of stays that may be very long. If your 90th percentile is two weeks, a
three-outcome model might make sense: Patients are
. Discharged within two weeks
. Died within two weeks
. Retained for stay longer than two weeks.
Changes in that last are meaningful, too.

Back to the denominator, the 'measure of exposure'. THAT depends on
your mortality model. One denominator for August would be the number of
patient-days in the hospital in August. That would be appropriate if,
say, most mortality was due to meteors falling through the roof and
hitting patients.

(OK, that's facetious. But it is based on the 'day' being the unit of
risk - that the mortality is strongly influenced by the length of stay,
itself. Try it, if you like: graph the percent of patients who are
there for day 1, 2, ... of their stays, die on that day. If it's fairly
constant, you have 'meteors'. But I doubt it will be. Likely, daily
risk of mortality declines a lot with length of stay: many admissions
are for acute conditions that resolve into discharge or death quite
soon; the longer-term chronic conditions are likely to drag on,
whatever the outcome.)

See what I mean? Apart from the problem of waiting for outcomes, what
denominator is appropriate depends on your risk model.

One more problem: "case-mix adjustment." That is, mortality partly
depends on how sick the patients are when they come in. That's commonly
resolved by classifying patients into categories like DRGs
("diagnostically related groups"), all of whose members should be
comparably 'sick'.
. If your case mix varies, mortality change may reflect that, rather
than anything the hospital does
. Even if the case mix doesn't vary, hospitals may be 'good' on some
types of case, poor on others. (As an extreme: Don't compare neonatal
intensive care patients with adult heart disease patients.) You may
need to break THAT down - requiring, of course, more data for reliable
conclusions.

There - that muddies the waters, at least. There's probably a point of
view from which your question has a simple, defensible answer; but as
posed, it raises more questions like these.

-Good luck,
  Richard Ristow
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Re: hospitals mortality rate

Jason Gillikin
In reply to this post by Omar Farook
Omar --

As someone who does this for a living, let me give you some ideas (the
comments from Richard Rostow notwithstanding).

1.  Depending on the size and complexity of your hospital, I'm not sure
you're going to derive much of value from a monthly analysis of morality
rates.  It's usually better to trend over more time, and to isolate for
specific mortality causes.  If you run a P-chart on a 500-bed hospital
that averages 40 deaths per month, but that hospital received two dozen
victims of a building fire who died in Emergency on one day, your "rate"
is going to appear to be out of control for that month.  Control charts
help to identify the presence of special-cause variation -- so trending
something without being sensitive to the variety of possible causes is
going to diminish the effectiveness of a control chart.  Might be better
to track, e.g., mortality ascribed to delays in medication
administration -- or at the least, to identify a few major groupings.

2.  In general, hospital mortality rates are relatively stable over the
long term, which is why a targeted QI effort based on specific causes of
in-house death usually makes more sense.

3.  My hospital (1,061 licensed beds over two facilities) reports
monthly deaths but does not get too worked up over variation in the
total.  We have dedicated QI efforts based on the causes of inpatient
death and track those instead (or proxy measures that can indicate
situations that can lead to avoidable death, such as the surgical
infection rate).

This does, however, start to move far afield from SPSS, so if you have
follow-up questions, please direct them to me by private e-mail.
Thanks, and good luck.

---
Jason E. Gillikin, CPHQ, Measurement & Evaluation Specialist
Access Management Department, MC 157 [640D Towers]
Spectrum Health - Grand Rapids Hospitals, 100 Michigan St. NE, Grand
Rapids MI  49503-2560
Tel/616.391.1639  |  Fax/616.391.3873  |  Cell/269.352.5615
[hidden email]  |  http://www.spectrum-health.org


-----Original Message-----
From: SPSSX(r) Discussion [mailto:[hidden email]]
Sent: Sunday, September 24, 2006 5:05 AM
To: [hidden email]
Subject: hospitals mortality rate

Q: Dear Experts,

I would like to monitor hospital's mortality rate in our hospital by
using p-control chart to see if the rates are within our expectation,
according to my knowledge mortality rate equation as follows,

Mortality rate = no. of patients who died / no. of patients admitted.

In a hospital we have a patient who admitted past month e.g. Aug and
died in Aug or sometimes in Sep.

My question is, if I would like to calculate mortality, rate let's say
for Aug, are the data for the numerator and denominator should be for
Aug only?

Hope I was clear enough and many thanks in advance.

Omar.


---------------------------------
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rates.
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Re: hospitals mortality rate

Marta García-Granero
In reply to this post by Richard Ristow
Hi all

Just my 2 €-cents (I happen to live in Europe, I think in euros, not in
dollars...)

Perhaps you could compute a true rate (strict definition: it involves
time) instead of a simple (or complicated, as it looks) proportion:

                            Number of cases in one month
Mortality rate= --------------------------------------------------
                 Sum of times of every patient during that month

This overcomes the problem of having to wait until a patient is
dicharged, or whether he/she entered the hospital the previous month
and therefore "belongs" to other month. The patient contributes to the
denominator with as many days of that month he/she's been admitted.

This measure is also called "density", as it gives the number of
deaths per person-time unit, and can be also looked as a "speed" of
death (since the denominator is time).

The corresponding model for this statistic is Poisson regression.

The drawback is that the rate can be interpreted only collectively, it
has no meaning when applied to a single individual.

HTH,
Marta

RR> At 01:55 AM 9/25/2006, Omar Farook wrote:

>>I think the equation of Mr. Ristow is very difficult to implement,
>>because
>>in this case may be we needs more than 3 months to wait until all
>>August's cases resolve (died or discharges).

RR> Well, then, you have to decide what you MEAN by "August mortality",
RR> starting by ignoring what you can and can't measure.

RR> In one way, apart from difficulties in measuring (the "three months to
RR> wait"), the definition I gave you is correct. What's probably
RR> meaningful to the patients and their families is, if someone is
RR> admitted to this hospital, what's the probability they will (ever) walk
RR> out alive?

RR> It may not be the right measure of hospital performance, though.

>>Now, David Wasserman <[hidden email]> suggsted:
>>
>>>Mortality rate for August = (all patients admitted in August who
>>>died)/(all
>>>patients admitted in August who died + all patients admitted in
>>>August who
>>>have been discharged) ignoring those who have neither died nor been
>>>discharged.

RR> That's a good idea, but it tacitly assumes that mortality for long-stay
RR> patients is similar to that for short-stay patients; at best, that
RR> can't be relied on. Much more likely, it isn't true.

RR> (I don't think this is a survival-analysis problem, by the way. A
RR> discharged patient isn't 'censored', but favorable-outcome.)

RR> Even if you can wait for all cases to be resolved, that's a problem:
RR> long-stay and short-stay patients likely have different mortality
RR> patterns. You should look, if you haven't. What is the distribution of
RR> your lengths of stay? What's the median, the 90th percentile, the 99th
RR> percentile? For a lot of hospitals, most stays are short, with a 'tail'
RR> of stays that may be very long. If your 90th percentile is two weeks, a
RR> three-outcome model might make sense: Patients are
RR> . Discharged within two weeks
RR> . Died within two weeks
RR> . Retained for stay longer than two weeks.
RR> Changes in that last are meaningful, too.

RR> Back to the denominator, the 'measure of exposure'. THAT depends on
RR> your mortality model. One denominator for August would be the number of
RR> patient-days in the hospital in August. That would be appropriate if,
RR> say, most mortality was due to meteors falling through the roof and
RR> hitting patients.

RR> (OK, that's facetious. But it is based on the 'day' being the unit of
RR> risk - that the mortality is strongly influenced by the length of stay,
RR> itself. Try it, if you like: graph the percent of patients who are
RR> there for day 1, 2, ... of their stays, die on that day. If it's fairly
RR> constant, you have 'meteors'. But I doubt it will be. Likely, daily
RR> risk of mortality declines a lot with length of stay: many admissions
RR> are for acute conditions that resolve into discharge or death quite
RR> soon; the longer-term chronic conditions are likely to drag on,
RR> whatever the outcome.)

RR> See what I mean? Apart from the problem of waiting for outcomes, what
RR> denominator is appropriate depends on your risk model.

RR> One more problem: "case-mix adjustment." That is, mortality partly
RR> depends on how sick the patients are when they come in. That's commonly
RR> resolved by classifying patients into categories like DRGs
RR> ("diagnostically related groups"), all of whose members should be
RR> comparably 'sick'.
RR> . If your case mix varies, mortality change may reflect that, rather
RR> than anything the hospital does
RR> . Even if the case mix doesn't vary, hospitals may be 'good' on some
RR> types of case, poor on others. (As an extreme: Don't compare neonatal
RR> intensive care patients with adult heart disease patients.) You may
RR> need to break THAT down - requiring, of course, more data for reliable
RR> conclusions.

RR> There - that muddies the waters, at least. There's probably a point of
RR> view from which your question has a simple, defensible answer; but as
RR> posed, it raises more questions like these.
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Re: hospitals mortality rate

Omar Farook
Dear Dr. Marta,

Kindly, is the numerator of the equation represent the No of patients died in one month regardless the date of admission, the current month or the past month.

Please, how could we calculate the denominator, what type of data we should look for?

Any references on how to deal with this equation will be appreciated.

Many thanks.

Omar.


Marta García-Granero <[hidden email]> wrote:  Hi all

Just my 2 €-cents (I happen to live in Europe, I think in euros, not in
dollars...)

Perhaps you could compute a true rate (strict definition: it involves
time) instead of a simple (or complicated, as it looks) proportion:

Number of cases in one month
Mortality rate= --------------------------------------------------
Sum of times of every patient during that month

This overcomes the problem of having to wait until a patient is
dicharged, or whether he/she entered the hospital the previous month
and therefore "belongs" to other month. The patient contributes to the
denominator with as many days of that month he/she's been admitted.

This measure is also called "density", as it gives the number of
deaths per person-time unit, and can be also looked as a "speed" of
death (since the denominator is time).

The corresponding model for this statistic is Poisson regression.

The drawback is that the rate can be interpreted only collectively, it
has no meaning when applied to a single individual.

HTH,
Marta

RR> At 01:55 AM 9/25/2006, Omar Farook wrote:

>>I think the equation of Mr. Ristow is very difficult to implement,
>>because
>>in this case may be we needs more than 3 months to wait until all
>>August's cases resolve (died or discharges).

RR> Well, then, you have to decide what you MEAN by "August mortality",
RR> starting by ignoring what you can and can't measure.

RR> In one way, apart from difficulties in measuring (the "three months to
RR> wait"), the definition I gave you is correct. What's probably
RR> meaningful to the patients and their families is, if someone is
RR> admitted to this hospital, what's the probability they will (ever) walk
RR> out alive?

RR> It may not be the right measure of hospital performance, though.

>>Now, David Wasserman suggsted:
>>
>>>Mortality rate for August = (all patients admitted in August who
>>>died)/(all
>>>patients admitted in August who died + all patients admitted in
>>>August who
>>>have been discharged) ignoring those who have neither died nor been
>>>discharged.

RR> That's a good idea, but it tacitly assumes that mortality for long-stay
RR> patients is similar to that for short-stay patients; at best, that
RR> can't be relied on. Much more likely, it isn't true.

RR> (I don't think this is a survival-analysis problem, by the way. A
RR> discharged patient isn't 'censored', but favorable-outcome.)

RR> Even if you can wait for all cases to be resolved, that's a problem:
RR> long-stay and short-stay patients likely have different mortality
RR> patterns. You should look, if you haven't. What is the distribution of
RR> your lengths of stay? What's the median, the 90th percentile, the 99th
RR> percentile? For a lot of hospitals, most stays are short, with a 'tail'
RR> of stays that may be very long. If your 90th percentile is two weeks, a
RR> three-outcome model might make sense: Patients are
RR> . Discharged within two weeks
RR> . Died within two weeks
RR> . Retained for stay longer than two weeks.
RR> Changes in that last are meaningful, too.

RR> Back to the denominator, the 'measure of exposure'. THAT depends on
RR> your mortality model. One denominator for August would be the number of
RR> patient-days in the hospital in August. That would be appropriate if,
RR> say, most mortality was due to meteors falling through the roof and
RR> hitting patients.

RR> (OK, that's facetious. But it is based on the 'day' being the unit of
RR> risk - that the mortality is strongly influenced by the length of stay,
RR> itself. Try it, if you like: graph the percent of patients who are
RR> there for day 1, 2, ... of their stays, die on that day. If it's fairly
RR> constant, you have 'meteors'. But I doubt it will be. Likely, daily
RR> risk of mortality declines a lot with length of stay: many admissions
RR> are for acute conditions that resolve into discharge or death quite
RR> soon; the longer-term chronic conditions are likely to drag on,
RR> whatever the outcome.)

RR> See what I mean? Apart from the problem of waiting for outcomes, what
RR> denominator is appropriate depends on your risk model.

RR> One more problem: "case-mix adjustment." That is, mortality partly
RR> depends on how sick the patients are when they come in. That's commonly
RR> resolved by classifying patients into categories like DRGs
RR> ("diagnostically related groups"), all of whose members should be
RR> comparably 'sick'.
RR> . If your case mix varies, mortality change may reflect that, rather
RR> than anything the hospital does
RR> . Even if the case mix doesn't vary, hospitals may be 'good' on some
RR> types of case, poor on others. (As an extreme: Don't compare neonatal
RR> intensive care patients with adult heart disease patients.) You may
RR> need to break THAT down - requiring, of course, more data for reliable
RR> conclusions.

RR> There - that muddies the waters, at least. There's probably a point of
RR> view from which your question has a simple, defensible answer; but as
RR> posed, it raises more questions like these.



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Re: hospitals mortality rate

Marta García-Granero
Hi Omar

Sorry for the delay, I didn't spot your message until now.

OF> Kindly, is the numerator of the equation represent the No of
OF> patients died in one month regardless the date of admission, the
OF> current month or the past month.

Yes

OF> Please, how could we calculate the denominator, what type of data we should look for?

It is the sum of the time (usually days) that patients stayed at
hospital during that given month.

Let's work with a small example: suppose you follow 5 patients (well
that's a very small hospital, but it's just an example) from the first
day to the last day of that month (let's say it's April, with 30 days):

Patient #1: Admitted day 5, released day 20 (15 days stay, no death).
Patient #2: Admitted day 3, died day 27 (24 days stay, death)
Patient #3: was admitted previous month, released day 13 (follow up
during that month: 13 days, no death)
Patient #4: was admitted previous month, died day 28 (follow up during
that month: 28 days, death)
Patient #5: admitted previous month, not released at the the end of
the month - still in hospital - (follow up: 30 days, no death).

The death rate in April would be:

Sum of deaths during that month: 2 (#2 & #4).
Sum of follow up times: 15+24+13+28+30=110 person-days

Death Rate = 2/110 = 0.0182 events/person-day

Anyway, I expect you'll be having a message from Richard Ristow very
soon (he wrote to me concerning this measure, and he didn't agree) :D

This in an epidemiological approach to your problem, I'll try to find
some references concerning its uses.

Regards,
Marta
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Re: hospitals mortality rate

Omar Farook
Dear Dr. Marta,

Good morning.

Kindly, how could we explain the 0.0182 events/person-day?

Many thanks.

Omar.
Marta García-Granero <[hidden email]> wrote:  Hi Omar

Sorry for the delay, I didn't spot your message until now.

OF> Kindly, is the numerator of the equation represent the No of
OF> patients died in one month regardless the date of admission, the
OF> current month or the past month.

Yes

OF> Please, how could we calculate the denominator, what type of data we should look for?

It is the sum of the time (usually days) that patients stayed at
hospital during that given month.

Let's work with a small example: suppose you follow 5 patients (well
that's a very small hospital, but it's just an example) from the first
day to the last day of that month (let's say it's April, with 30 days):

Patient #1: Admitted day 5, released day 20 (15 days stay, no death).
Patient #2: Admitted day 3, died day 27 (24 days stay, death)
Patient #3: was admitted previous month, released day 13 (follow up
during that month: 13 days, no death)
Patient #4: was admitted previous month, died day 28 (follow up during
that month: 28 days, death)
Patient #5: admitted previous month, not released at the the end of
the month - still in hospital - (follow up: 30 days, no death).

The death rate in April would be:

Sum of deaths during that month: 2 (#2 & #4).
Sum of follow up times: 15+24+13+28+30=110 person-days

Death Rate = 2/110 = 0.0182 events/person-day

Anyway, I expect you'll be having a message from Richard Ristow very
soon (he wrote to me concerning this measure, and he didn't agree) :D

This in an epidemiological approach to your problem, I'll try to find
some references concerning its uses.

Regards,
Marta



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Re: hospitals mortality rate

Marta García-Granero
Hi Omar

The key is understanding these concepts:

Person-time: A measurement combining persons and time, used as a
denominator in person-time incidence and mortality rates. It is the
sum of individual units of time that the persons in the study
population have been exposed to the condition of interest. A variant
is person-distance, e.g., as in passenger-kilometers. The most
frequently used person-time is person-years. With this approach, each
subject contributes only as many years of observation to the
population at risk as he is actually observed; if he leaves after 1
year, he contributes 1 person-year; if after 10, 10 person-years. The
method can be used to measure incidence over extended and variable
time periods.

Rate: the number of cases developing per unit time

(from: http://www.cbtrus.org/glossary/glossary2.html )

OF> Kindly, how could we explain the 0.0182 events/person-day?

We can multiply & divide it by 1000:

Event Rate =18.2 events /1000 person-day

As I mentioned in a previous mail, this figure has no individual
interpretation (we can't assimilate it to the probability a certain
patient dies) but collective: we might expect 18 deaths when we have a
total follow-up time of 1000 patients-days. This 1000 patients-days
can be the result of 1000 patients followed 1 day, or 200 patients
followed 5 days, or some patients being followed for more time than
others. It has the advantage that all the information from each patient
is taken into account (event if they were admitted the previous month,
or hasn't be discharged by the end of this month...). It also takes
into account not only the number of patients admitted, but also the
time they stayed.

OF> Let's work with a small example: suppose you follow 5 patients
OF> (well that's a very small hospital, but it's just an example) from
OF> the first day to the last day of that month (let's say it's April,
OF> with 30 days):

OF> Patient #1: Admitted day 5, released day 20 (15 days stay, no death).
OF> Patient #2: Admitted day 3, died day 27 (24 days stay, death)
OF> Patient #3: was admitted previous month, released day 13 (follow up
OF> during that month: 13 days, no death)
OF> Patient #4: was admitted previous month, died day 28 (follow up during
OF> that month: 28 days, death)
OF> Patient #5: admitted previous month, not released at the the end of
OF> the month - still in hospital - (follow up: 30 days, no death).

OF> The death rate in April would be:

OF> Sum of deaths during that month: 2 (#2 & #4).
OF> Sum of follow up times: 15+24+13+28+30=110 person-days

OF> Death Rate = 2/110 = 0.0182 events/person-day

HTH,
Marta
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Re: hospitals mortality rate

Richard Ristow
In reply to this post by Marta García-Granero
At 05:21 AM 9/30/2006, Marta García-Granero wrote:

>>OF> Kindly, is the numerator of the equation
>>represent the No of patients died in one month
>>regardless the date of admission, the current month or the past month.
>
>Yes
>
>>OF> Please, how could we calculate the
>>denominator, what type of data we should look for?
>
>It is the sum of the time (usually days) that
>patients stayed at hospital during that given month.
>
>Anyway, I expect you'll be having a message from
>Richard Ristow very soon (he wrote to me
>concerning this measure, and he didn't agree) :D

Well, this isn't very soon - I've been off for
the last couple of days. Among other things,
Narragansett Bay under sail is even better than
the Net. But, yes, this is a dissenting opinion.

For human decision-making, measures of risk
should reflect what matters to those who bear or
pay for the consequences; for best understanding,
they should seek sensitivity to the risk
mechanisms, and insensitivity to extraneous factors.

The risks of SOME ill occurrences in hospitals
are broadly constant per patient-day, and
increase accordingly with length of stay:
hospital-acquired infections, certain kinds of
medical error. Hospital performance on these
should be (and is) assessed per patient-day.

But hospitals exist to discharge patients alive
and well, not to have them survive the most
possible days in hospital. There are serious
paradoxes in the patient-day measure: If average
length of stay declines (as it has, dramatically,
over the last decade or so), and mortality per
admission declines but less rapidly, mortality
per patient-day will rise despite what's overall a clear improvement.

By analogy, consider air travel: Safety is not
measured per passenger-mile or per
passenger-hour, but per passenger. Partly, that
mirrors passengers' interest: "Am I going to get
off this thing alive?" Partly, it reflects the
actual risks of flying, which are much more
per-flight - takeoffs and landings - than per-mile or per-hour.

(In all this, by the way, I've left out "case
mix" issues: Patients are not all comparable, and
hospital outcomes very dramatically by patient
age, economic status, and particularly cause of
admission. I've left out these issues, but if
you're assessing hospitals, you'd better not.)
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Re: hospitals mortality rate

Omar Farook
In reply to this post by Marta García-Granero
Dear Dr. Marta,

Good morning.

Suppose we have a monthly data, could we say that

we might expect 18 deaths if we follow-up 33 patient 30 days?

Many thanks.

Omar.


Marta García-Granero <[hidden email]> wrote:   Hi Omar

The key is understanding these concepts:

Person-time: A measurement combining persons and time, used as a
denominator in person-time incidence and mortality rates. It is the
sum of individual units of time that the persons in the study
population have been exposed to the condition of interest. A variant
is person-distance, e.g., as in passenger-kilometers. The most
frequently used person-time is person-years. With this approach, each
subject contributes only as many years of observation to the
population at risk as he is actually observed; if he leaves after 1
year, he contributes 1 person-year; if after 10, 10 person-years. The
method can be used to measure incidence over extended and variable
time periods.

Rate: the number of cases developing per unit time

(from: http://www.cbtrus.org/glossary/glossary2.html )

OF> Kindly, how could we explain the 0.0182 events/person-day?

We can multiply & divide it by 1000:

Event Rate =18.2 events /1000 person-day

As I mentioned in a previous mail, this figure has no individual
interpretation (we can't assimilate it to the probability a certain
patient dies) but collective: we might expect 18 deaths when we have a
total follow-up time of 1000 patients-days. This 1000 patients-days
can be the result of 1000 patients followed 1 day, or 200 patients
followed 5 days, or some patients being followed for more time than
others. It has the advantage that all the information from each patient
is taken into account (event if they were admitted the previous month,
or hasn't be discharged by the end of this month...). It also takes
into account not only the number of patients admitted, but also the
time they stayed.

OF> Let's work with a small example: suppose you follow 5 patients
OF> (well that's a very small hospital, but it's just an example) from
OF> the first day to the last day of that month (let's say it's April,
OF> with 30 days):

OF> Patient #1: Admitted day 5, released day 20 (15 days stay, no death).
OF> Patient #2: Admitted day 3, died day 27 (24 days stay, death)
OF> Patient #3: was admitted previous month, released day 13 (follow up
OF> during that month: 13 days, no death)
OF> Patient #4: was admitted previous month, died day 28 (follow up during
OF> that month: 28 days, death)
OF> Patient #5: admitted previous month, not released at the the end of
OF> the month - still in hospital - (follow up: 30 days, no death).

OF> The death rate in April would be:

OF> Sum of deaths during that month: 2 (#2 & #4).
OF> Sum of follow up times: 15+24+13+28+30=110 person-days

OF> Death Rate = 2/110 = 0.0182 events/person-day

HTH,
Marta



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