Clearly, it does not address the problem of unequal values for Pre, between groups.
That raises a problem of logical conclusions, even if the MIXED test works okay as a test.
Clearly, it will be inferior testing compared to testing a simple, natural transformation
of the measures, when that is what the data cry out for.
- Those are the two big considerations that jump to my mind.
It would be nice to know what situations have this as the ideal approach; and to know what
other assumptions there are for this approach, and how serious it is to violate them.
--
Rich Ulrich> Date: Wed, 27 Apr 2016 10:32:40 -0700
> From: [hidden email]
> Subject: Re: 2way mixed ANOVA significant interaction, but main effects not significant. What does this mean
> To: [hidden email]
>> Another way to handle heterogeneity of variance is to estimate the model via
> MIXED, allowing for heterogeneous group variances. See below.
>
> * ANCOVA with DV = post, covariate = pre estimated in the usual way.
>
> UNIANOVA post BY grp WITH pre
> /PRINT = parameter
> /EMMEANS = table(grp)
> /DESIGN = pre grp
> .
>
> * Same model via MIXED.
>
> MIXED post BY grp WITH pre
> /FIXED=pre grp | SSTYPE(3)
> /PRINT=SOLUTION TESTCOV
> /EMMEANS = tables(grp)
> .
>
> * Now include /REPEATED sub-command to
> * allow for heterogenous group variances.
>
> MIXED post BY grp WITH pre
> /FIXED=pre grp | SSTYPE(3)
> /PRINT=SOLUTION TESTCOV
> /REPEATED=grp | SUBJECT(ID) COVTYPE(DIAG)
> /EMMEANS = tables(grp)
> .
>
> HTH.
>
>
> Rich Ulrich wrote
> > There is a ton of literature on the subject of analyzing change.
> > Unfortunately,
> > much of it is not very well informed. On a quick Google, I found that the
> > first
> > answer at the URL below (the Reply referencing Senn) gives a pretty good
> > overview,
> > plus references. (The Reply-er endorses using ANCOVA for controlled
> > studies.)
> >
> > http://stats.stackexchange.com/questions/3466/best-practice-when-analysing-pre-post-treatment-control-designs
> >
> > I will add:
> > On assumptions: It is nice to have (1) equal variances everywhere, (2)
> > equal means at Pre, and
> > (3) a shared regression line. Given those, it is hard to fault the
> > ANCOVA. In my experience,
> > "unequal variances" are sometimes fixed by suitable transformation of the
> > criterion. But the
> > failure of the assumptions is why (at least, in my off-hand thoughts here)
> > you might want to
> > analyze the Outcome while ignoring Pre, or analyze the simple change
> > score. Unequal-at-Pre
> > raises serious logical conundrums, at times, and
> > regression-not-to-the-shared-mean on top of
> > unequal-at-Pre puts you into statistical complication, and controversy.
> > The latter was the case
> > of analyzing long-term outcome for Headstart vs. other students -- where
> > Expected outcome with
> > no intervention, according to other experience, would be that the
> > lower-achieving target cases
> > should fall further and further behind.
> >
> > --
> > Rich Ulrich
> >
> > --- snip ---
>
>
>
>
>
> -----
> --
> Bruce Weaver
> [hidden email]
> http://sites.google.com/a/lakeheadu.ca/bweaver/
>
> "When all else fails, RTFM."
>
> NOTE: My Hotmail account is not monitored regularly.
> To send me an e-mail, please use the address shown above.
>
> --
> View this message in context: http://spssx-discussion.1045642.n5.nabble.com/2way-mixed-ANOVA-significant-interaction-but-main-effects-not-significant-What-does-this-mean-tp5732027p5732051.html
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