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Re: Linear Mixed Model in SPSS Guidance

Posted by msherman on Apr 23, 2019; 5:30pm
URL: http://spssx-discussion.165.s1.nabble.com/Linear-Mixed-Model-in-SPSS-Guidance-tp5737698p5737706.html

Randomization was used with 100 per treatment group. The two groups were equated on all demos and on the pretest. The age variable was equal between the two treatment groups before creating the binary age variable (of special interest to the PI-younger vs. older).  All pretest score distributions and post test scores distribution are bell shaped with some outliers for both groups. 


From: Rich Ulrich <[hidden email]>
Sent: Tuesday, April 23, 2019 12:00 PM
To: [hidden email]; Martin Sherman
Subject: Re: Linear Mixed Model in SPSS Guidance

 

Books have been written about the analysis of change scores. The choices

may be described as "change" (repeated measures), "regressed change"

(ANCOVA), and "other" (special, awkward considerations that hopefully

do not arise).

 

The problems for inference that are most frequent arise when the

initial groups are not matched on the Outcome score -- And you have

Age as a factor, which is very often correlated with everything. Is that

a problem for your data? (Of course, there also should be Random

assignment to the treatments shown by similar means for those

groups, or the inference problem is even worse.)

 

When initial scores are not matched, THEN, especially, you  need to worry

that the "scaling" of an outcome might be "wrong" so that it introduces

apparent effects that are artifacts of scoring. 

 

Artifacts: For instance, if everybody doubles their score from Pre to Post

on a scale where you should have taken the logs, then the initially-higher

scoring group will show greater change. Or, the opposite, for a scale with

a max:  If there is a "ceiling effect", then the initially-higher group has

little room to improve and will show less change.

 

--

Rich Ulrich

 


From: SPSSX(r) Discussion <[hidden email]> on behalf of Martin Sherman <[hidden email]>
Sent: Tuesday, April 23, 2019 9:00 AM
To: [hidden email]
Subject: Linear Mixed Model in SPSS Guidance

 

Dear List:  I am working on  pretest/post-test study with two between group factors, Treatment (Therapy A vs. Therapy B) and Age (younger vs. Older) on various outcome variables (all continuous). I originally considered doing a  repeated measures analysis but after reading up on the pros and cons of such an analysis I decided that a linear mixed model would be more appropriate given the correlation between the pre-test scores and the post-test scores. To further my understanding I reviewed the text by Verbeke and Molenberghs (Linear Mixed Models for Longitudinal Data). Getting through the text proved to be a challenge (many many equations beyond my pay grade). So I starting looking for some dummy downed explanations on how to set up my statistical model. So far that have not generated any comparable examples of my design  (2 x 2 x (2)). I am hoping there are some folks on the listserve that might be able to point me in some directions that will prove to be beneficial. I have googled but I have not found any helpful tutorials. Per chance if anyone has a good tutorial for my design I would appreciate hearing from you.  Thanks,  martin sherman

 

Martin F. Sherman, Ph.D.

Professor of Psychology

Loyola University Maryland

4501 North Charles Street

222 B Beatty Hall

Baltimore, MD 21210

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===================== To manage your subscription to SPSSX-L, send a message to [hidden email] (not to SPSSX-L), with no body text except the command. To leave the list, send the command SIGNOFF SPSSX-L For a list of commands to manage subscriptions, send the command INFO REFCARD