Login  Register

conditional logistic regression

Posted by C_visser on Mar 31, 2021; 8:55am
URL: http://spssx-discussion.165.s1.nabble.com/conditional-logistic-regression-tp5740363.html

Dear everyone,

I am trying to use a conditional logistic regression in SPSS. I am using
SPSS version 25. I have looked at a lot of youtube videos explaining the
cox-regression method, but something is going wrong as it seems it is
censoring too many cases. I think this is due to our study design and
studied exposures, but I am not entirely sure (as I am just a beginner). Our
study design is the following:

We have participants with an certain exposure and want to compare their
measurements of certain values before the exposure and afterwards. In this
study they will receive this exposure two times. So we want to compare a
certain variable at the time before the exposure, the time between the first
and second exposure and after the second exposure. As we are measuring these
variables in the same subjects, we think we should use a cross-over design
and paired statics tests. Right now, I want to see if the subjects after the
first and second exposure have a higher risk of a certain complication
compared to before the exposure. An epidemiologist suggested using a
conditional logistic regression.

We have tried to do this test in spss by using the cox regression method. We
have coded a casecontrol variable (before exposure = 2, after exposure = 1)
as time, the depent variable as a categorical variable with 0 = no
complication, 1 = complication, timing as covariate (0 = before exposure; 1
= after exposure) and paired the measurement before and after exposure in
the same subject using an identical identifier. However, when I compare the
outcome with the mcnemar test it is not the same. Also it seems like spss is
running the test on a smaller number of subjects than I expected.

Can somebody help me with this problem?

Kind regards,

Chantal



--
Sent from: http://spssx-discussion.1045642.n5.nabble.com/

=====================
To manage your subscription to SPSSX-L, send a message to
[hidden email] (not to SPSSX-L), with no body text except the
command. To leave the list, send the command
SIGNOFF SPSSX-L
For a list of commands to manage subscriptions, send the command
INFO REFCARD