Are the group samples or populations? If they are sample you could run a Hypothesis Test for Difference Between Proportions, but if they are populations I do not think you need to run any test.
Concerning the number of physicians's base, again: if you have samples of larger group you *could* run hypothesis testing - depending on your substantive research questions, but if you have populations probably all you can do is to compute other indexes - i.e. (15000-1200)/1600 vs (6500000-260000)/16000000 to see if the G1's physicians are possibly more effective than G2's physicians to help with disease's prevention/cure.
HTH,
Luca
Mr. Luca Meyer
www.lucameyer.com